Medically reviewed by Alan Carter, Pharm.D. — Written by Crystal Raypole on May 17, 2019
The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s by researchers exploring THC, a well-known cannabinoid. Cannabinoids are compounds found in cannabis. Experts are still trying to fully understand the ECS. But so far, we know it plays role in regulating a range of functions and processes, including: sleep, mood, appetite, memory reproduction and fertility. The ECS exists and is active in your body even if you don’t use cannabis.
The ECS involves three core components: endocannabinoids, receptors, and enzymes.
Endocannabinoids
Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body. They’re similar to cannabinoids, but they’re produced by your body. Experts have identified two key endocannabinoids so far: anandamide (AEA) and 2-arachidonoylglyerol (2-AG). These help keep internal functions running smoothly. Your body produces them as needed, making it difficult to know what typical levels are for each.
Endocannabinoid receptors…